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Anti-Mouse CD276/B7-H3 Antibody (m276), APC (MV612237)

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Overview

Catalog No.	MV612237
Description	Anti-Mouse CD276/B7-H3 Antibody (m276), APC [m276] (MV612237) is a rat monoclonal antibody detecting B7-H3 in FCM. Suitable for Human, Mouse, and Rat. Highlights ●Flow Cytometry — Validated for flow cytometry applications. ●Fluorescent Label — Direct conjugate for streamlined workflows. ●Multi-Species — Cross-reactive for translational research.
Species reactivity	Human, Mouse, Rat
Applications	FCM
Host species	Rat
Isotype	IgG1, kappa
Clone ID	m276
Conjugation	APC
Clonality	Monoclonal
Target	CD276, B7-H3, Costimulatory molecule, B7H3, 4Ig-B7-H3, B7 homolog 3, CD276 antigen
Endotoxin level	Please contact with the lab for this information.
Accession	Q8VE98
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	CD276 antigen (B7-H3) is a ~34 kDa protein. Modulates T-cell-mediated immune responses and the development of acute and chronic transplant rejection. Plays a positive regulatory role in bone formation and has a dual role in the bone-immune interface. Induces antitumor immunity as it activates both acquired and innate immunity leading to natural killer cell and CD8 T-cell dependent killing of tumor cells. CD276 is the therapeutic target of omburtamab (clinical).
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Datasheet

Anti-Mouse CD276/B7-H3 Antibody (m276), APC.pdf

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Anti-Mouse CD276/B7-H3 Antibody (m276), APC