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Anti-Mouse SORD Polyclonal Antibody (MX841014)

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Overview
Catalog No.MX841014
Description
Anti-Mouse SORD Polyclonal Antibody (MX841014) is a rabbit polyclonal antibody detecting SORD. Suitable for Rat and Mouse.
Highlights
  • Multi-Species — Cross-reactive for translational research.
Species reactivityMouse, Rat
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Mouse SORD (Met1-Pro357).
Target (R,R)-butanediol dehydrogenase, EC:1.1.1.-, EC:1.1.1.14, EC:1.1.1.4, EC:1.1.1.56, EC:1.1.1.9, L-iditol 2-dehydrogenase, Polyol dehydrogenase, RDH, Ribitol dehydrogenase, SDH, SORD, Sorbitol dehydrogenase, XDH, Xylitol dehydrogenase
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q64442
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Sorbitol dehydrogenase (SORD) is a ~38 kDa protein. Polyol dehydrogenase that catalyzes the reversible NAD(+)-dependent oxidation of various sugar alcohols. Is active with D-sorbitol (D-glucitol) leading to the C2-oxidized product D-fructose. Is a key enzyme in the polyol pathway that interconverts glucose and fructose via sorbitol, which constitutes an important alternate route for glucose metabolism. May play a role in sperm motility by using sorbitol as an alternative energy source for sperm motility and protein tyrosine phosphorylation. Has no activity on ethanol.

1. Burnell, JN. et al. (1983) The International journal of biochemistry 15, 507-11. PMID: 6852349
2. Cao, W. et al. (2009) Biology of reproduction 80, 124-33. PMID: 18799757
Note For research use only
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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