Anti-Mouse STAT3 Recombinant Antibody (SAA0274) (MW708013)

Name: Anti-Mouse STAT3 Recombinant Antibody (SAA0274)
Brand: abinScience
SKU: MW708013
Price: 196 USD
Availability: InStock

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50ug
100ug
1mg

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

MW708013

Species reactivity

Human, Mouse

Applications

ELISA, IP, WB

Host species

Rat

Isotype

IgG1, kappa

Clone ID

SAA0274

Clonality

Monoclonal

Target

Signal transducer and activator of transcription 3, APRF, STAT3, Acute-phase response factor

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P42227

RRID

Anti-Mouse STAT3 Antibody (SAA0274) (abinScience Cat# MW708013, RRID:AB_3725645)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Signal transducer and activator of transcription 3 (STAT3) is a ~88 kDa protein. Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors. Once activated, recruits coactivators, such as NCOA1 or MED1, to the promoter region of the target gene. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Upon activation of IL6ST/gp130 signaling by interleukin-6 (IL6), binds to the IL6-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA.

1. Ren, F. et al. (2013) Cellular signalling 25, 2272-80. PMID: 23917203

2. Ren, F. et al. (2015) FEBS letters 589, 1890-6. PMID: 26026268

3. Bates, SH. et al. (2003) Nature 421, 856-9. PMID: 12594516

4. Gonzalez, RR. et al. (2006) The Journal of biological chemistry 281, 26320-8. PMID: 16825198

5. Kostromina, E. et al. (2010) Endocrinology 151, 2050-9. PMID: 20215569

6. Manukyan, I. et al. (2010) Journal of cellular and molecular medicine 14, 1707-16. PMID: 19538478

7. Choi, SM. et al. (2013) The Journal of experimental medicine 210, 551-61. PMID: 23401489

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Mouse STAT3 Antibody (SAA0274)

References

Datasheet

Anti-Mouse STAT3 Recombinant Antibody (SAA0274).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Mouse STAT3 Recombinant Antibody (SAA0274) (MW708013)

Overview

Images

References

Datasheet

SDS

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