Mouse STAT3 Recombinant Protein (N-GST) (MW708012)

Name: Mouse STAT3 Recombinant Protein (N-GST)
Brand: abinScience
SKU: MW708012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	MW708012
Description	Recombinant Mouse STAT3 Protein, N-GST (MW708012) expressed in E. coli, spanning Met1-Met770. Purity: >90% by SDS-PAGE. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	P42227
Protein length	Met1-Met770
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Mus musculus (Mouse)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	114.35 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. RECONSTITUTION PROTOCOL 1. Allow the product to be reconstituted and the reconstitution diluent to reach room temperature. 2. Tap or briefly centrifuge the product vial before opening to dislodge any lyophilized material that may be dispersed on the wall or cap of the vial. 3. Use the diluent and stock concentration recommended in the product datasheet. If preparing a stock concentration higher than recommended, contact Technical Service. 4. After adding the diluent, re-cap the vial and invert gently by hand or place on a slow rocking platform to allow the reconstitution diluent to coat all the surfaces inside the vial. Note: Do not mix by vortexing or by pipetting the material up and down. 5. Allow the vial to sit at room temperature with gentle agitation for at least 15 minutes before aliquotting or using. 6. Store the reconstituted material in single use aliquots in polypropylene or siliconized tubes. Aliquots of 10 μL or larger are recommended.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	Signal transducer and activator of transcription 3, APRF, STAT3, Acute-phase response factor
Background	Signal transducer and activator of transcription 3 (STAT3) is a ~88 kDa protein. Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors. Once activated, recruits coactivators, such as NCOA1 or MED1, to the promoter region of the target gene. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Upon activation of IL6ST/gp130 signaling by interleukin-6 (IL6), binds to the IL6-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA. 1. Ren, F. et al. (2013) Cellular signalling 25, 2272-80. PMID: 23917203 2. Ren, F. et al. (2015) FEBS letters 589, 1890-6. PMID: 26026268 3. Bates, SH. et al. (2003) Nature 421, 856-9. PMID: 12594516 4. Gonzalez, RR. et al. (2006) The Journal of biological chemistry 281, 26320-8. PMID: 16825198 5. Kostromina, E. et al. (2010) Endocrinology 151, 2050-9. PMID: 20215569 6. Manukyan, I. et al. (2010) Journal of cellular and molecular medicine 14, 1707-16. PMID: 19538478 7. Choi, SM. et al. (2013) The Journal of experimental medicine 210, 551-61. PMID: 23401489
Note	For research use only.

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SDS-PAGE for Recombinant Mouse STAT3 Protein, N-GST

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Datasheet

Mouse STAT3 Recombinant Protein (N-GST).pdf

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Mouse STAT3 Recombinant Protein (N-GST) (MW708012)

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