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Anti-Mouse TMEM87A Monoclonal Antibody (1A230) (MA270015)

Anti-Mouse TMEM87A Monoclonal Antibody (1A230)
Anti-Mouse TMEM87A Monoclonal Antibody (1A230)
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Overview
Catalog No.MA270015
Description
Anti-Mouse TMEM87A Monoclonal Antibody (1A230) [1A230] (MA270015) is a rat monoclonal antibody detecting TMEM87A in ELISA, WB. Suitable for Mouse.
Highlights
  • Recombinant — Superior batch-to-batch reproducibility with defined sequences.
Species reactivityMouse
ApplicationsELISA, WB
Host speciesRat
IsotypeIgG2a
Clone ID1A230
Clonality Monoclonal
Immunogen Recombinant Mouse TMEM87A protein.
Target Transmembrane protein 87A, Elkin1, TMEM87A, PSEC0094
Purification Protein A/G purified from cell culture supernatant.
Accession Q8BXN9
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Transmembrane protein 87A (TMEM87A) is a ~63 kDa protein. Potential monoatomic ion channel gated by mechanical force, implicated in normal touch sensitivity through the generation of mechanically activated currents. However, a direct channel activity is debated and an alternative could be that it functions as a chaperone for an unidentified mechanosensitive ion channel. Could also be involved in cell mechanosensitivity regulating cell adhesion and migration. May also be involved in retrograde transport from endosomes to the trans-Golgi network (TGN).

1. Chakrabarti, S. et al. (2024) Science (New York, N.Y.) 383, 992-998. PMID: 38422143
2. Patkunarajah, A. et al. (2020) eLife 9. PMID: 32228863
Note For research use only.
Images
  • Anti-Mouse TMEM87A Monoclonal Antibody (1A230)

    SDS-PAGE

    SDS-PAGE for Anti-Mouse TMEM87A Monoclonal Antibody (1A230)

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
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Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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