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Anti-Mycoplasma pneumoniae Wheel complex protein P41 Polyclonal Antibody (JN180034)

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Overview
Catalog No.JN180034
Description
Anti-Mycoplasma pneumoniae Wheel complex protein P41 Polyclonal Antibody (JN180034) is a rabbit polyclonal antibody detecting Wheel complex protein P41. Suitable for Mycoplasma pneumoniae.
Species reactivityMycoplasma pneumoniae
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Mycoplasma pneumoniae Wheel complex protein P41 (Met1-Gln220).
Target Cytoskeletal protein P41, Wheel complex protein P41
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession P75470
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Wheel complex protein P41 is a ~40 kDa protein. Stably anchors the attachment organelle to the cell body and for their spatial positioning. Required for stable accumulation of P28 (also called HMW2-s, a short protein produced by upstream MPN_310). Required for correct localization of P24. Ectopic expression of P41 restores gliding velocity but not gliding frequency to a P41-P24 disruption, attachment organelles do not initiate as frequently as in wild-type; inclusion of P24 restores a wild-type phenotype. May play a role in attachment organelle initiation and its coordination with the cell cycle (Probable).

1. Hasselbring, BM. et al. (2007) Molecular microbiology 63, 44-53. PMID: 17163973
2. Hasselbring, BM. et al. (2007) Journal of bacteriology 189, 7442-9. PMID: 17693502
3. Nakane, D. et al. (2015) PLoS pathogens 11, e1005299. PMID: 26633540
Note For research use only
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Formula
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