Anti-Nipah virus/NiV F/Fusion glycoprotein F0 Antibody (SAA2759) (VK521073)

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Spec:

50ug
100ug
1mg

Number:

Overview
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Datasheet

Overview

Catalog No.

VK521073

Description

Anti-Nipah virus/NiV F/Fusion glycoprotein F0 Antibody (SAA2759) (VK521073) is a mouse monoclonal antibody detecting Fusion glycoprotein F0. Suitable for Nipah viurs.

Species reactivity

Nipah viurs

Applications

ELISA, Neutralization

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA2759

Clonality

Monoclonal

Target

F, Fusion glycoprotein F0, Fusion glycoprotein F1, Fusion glycoprotein F2, Protein F

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9IH63

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Fusion glycoprotein F0 (Fusion protein) is a ~60 kDa protein. Class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and plasma cell membrane fusion, the heptad repeat (HR) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and plasma cell membranes. Directs fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm.

Note

For research use only

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References

Datasheet