Anti-Nivolumab Polyclonal Antibody (AS870024)

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Overview

Catalog No.

AS870024

Description

Anti-Nivolumab Polyclonal Antibody (AS870024) is a rabbit polyclonal antibody detecting Nivolumab in ELISA.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.

Applications

ELISA

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

Nivolumab

Tested applications

ELISA

Target

Nivolumab, BMS-936558, MDX-1106, MDX1106, MDX 1106, ONO-4538, OPDIVO

Specificity

The product is specific for Nivolumab. This antibody serves as an excellent positive control for Nivolumab immunogenicity (ADA) assays.

Endotoxin level

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

The product can be stored for 2 - 3 weeks at 2 to 8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles.

Background

Nivolumab (Opdivo) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of patients with unresectable or metastatic melanoma. Nivolumab binds to the human cell surface receptor PD-1 (Programmed Cell Death Protein 1) and blocks its interaction with PD-L1, resulting in the activation of T-cell-mediated immune responses against tumor cells. Antibodysystem Anti-Nivolumab Antibody, pAb, Rabbit is produced from sera of a rabbit immunized with Nivolumab.

Note

For research use only.

Images

References

Datasheet

Anti-Nivolumab Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Nivolumab Polyclonal Antibody (AS870024)

Overview

Images

References

Datasheet

SDS

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