Anti-NK1R Recombinant Antibody (N188/19) (HB146013)

Name: Anti-NK1R Recombinant Antibody (N188/19)
Brand: abinScience
SKU: HB146013
Price: 196 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HB146013

Description

Anti-NK1R Recombinant Antibody (N188/19) (HB146013) is a mouse monoclonal antibody detecting NK1R in IHC, WB.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Applications

IHC, WB

Host species

Mouse

Clonality

Monoclonal

Isotype

IgG2a, kappa

Clone ID

N188/19

Target

TAC1R, Tachykinin receptor 1, NK-1R, NK1R, SPR, TACR1, Substance-P receptor, NK-1 receptor

Endotoxin level

< 10 EU/mg as determined by LAL method.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

RRID

Anti-NK1R Antibody (N188/19) (abinScience Cat# HB146013, RRID:AB_3728175)
_x005F_x000D_

Form

Liquid

Storage buffer

0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Substance-P receptor (TACR1/NK-1R) is a ~46 kDa protein. Receptor for the tachykinin substance P, also able to bind and respond to tachynins neurokinin A/substance K and neurokinin B/neuromedin-K. The rank order of affinity of this receptor to tachykinins is: substance P > neurokinin A/substance K > neurokinin B/neuromedin-K. Substance P binding to its receptor triggers G protein-coupled receptor signaling via activation of phosphatidylinositol hydrolysis by phospholipase C. Substance P binding also triggers signaling via activation of adenylate cyclase activity which results in increased intracellular levels of cyclic AMP (cAMP).

1. Takeda, Y. et al. (1991) Biochemical and biophysical research communications 179, 1232-40. PMID: 1718267

2. Randolph, GP. et al. (2004) The pharmacogenomics journal 4, 394-402. PMID: 15452552

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-NK1R Antibody (N188/19)

References

Datasheet

Anti-NK1R Recombinant Antibody (N188/19).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-NK1R Recombinant Antibody (N188/19) (HB146013)

Overview

Images

References

Datasheet

SDS