Anti-P2X4 Recombinant Antibody (N368/12) (HP943013)

Name: Anti-P2X4 Recombinant Antibody (N368/12)
Brand: abinScience
SKU: HP943013
Price: 196 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HP943013

Description

Anti-P2X4 Recombinant Antibody (N368/12) (HP943013) is a mouse monoclonal antibody detecting P2X4 in IHC, WB.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Applications

IHC, WB

Host species

Mouse

Clonality

Monoclonal

Isotype

IgG2a, kappa

Clone ID

N368/12

Target

Purinergic receptor, P2RX4, P2X4, P2X purinoceptor 4, ATP receptor

Endotoxin level

< 10 EU/mg as determined by LAL method.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

RRID

Anti-P2X purinoceptor 4 Antibody (N368/12) (abinScience Cat# HP943013, RRID:AB_3728288)
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Form

Liquid

Storage buffer

0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

P2X purinoceptor 4 (P2RX4) is a ~43 kDa protein. ATP-gated nonselective transmembrane cation channel permeable to potassium, sodium and calcium. CTP, but not GTP or UTP, functions as a weak affinity agonist for P2RX4. Activated by extracellularly released ATP, it plays multiple role in immunity and central nervous system physiology. Plays a key role in initial steps of T-cell activation and Ca(2+) microdomain formation. Also participates in basal T-cell activity without TCR/CD3 stimulation.

1. Garcia-Guzman, M. et al. (1997) Molecular pharmacology 51, 109-18. PMID: 9016352

2. Hamoudi, C. et al. (2022) Journal of immunology (Baltimore, Md. : 1950) 208, 1115-1127. PMID: 35165166

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-P2X purinoceptor 4 Antibody (N368/12)

References

Datasheet

Anti-P2X4 Recombinant Antibody (N368/12).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-P2X4 Recombinant Antibody (N368/12) (HP943013)

Overview

Images

References

Datasheet

SDS