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Anti-Plasmodium falciparum CSP Recombinant Antibody (AB-007088) (JN160083)

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Overview
Catalog No.JN160083
Description
Anti-Plasmodium falciparum CSP Recombinant Antibody (AB-007088) (JN160083) is a monoclonal antibody detecting CSP in ELISA, Function assay. Suitable for Plasmodium falciparum.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Species reactivityPlasmodium falciparum
ApplicationsELISA, Function assay
ClonalityMonoclonal
Clone IDAB-007088
Target CS, CSP, Circumsporozoite protein, Circumsporozoite protein C-terminus, PfCSP
Endotoxin level < 10 EU/mg as determined by LAL method.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q7K740
Form Liquid
Storage buffer 0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Circumsporozoite protein is a ~42 kDa protein. Essential sporozoite protein. In the mosquito vector, required for sporozoite development in the oocyst, migration through the vector hemolymph and entry into the vector salivary glands. In the vertebrate host, required for sporozoite migration through the host dermis and infection of host hepatocytes. Binds to highly sulfated heparan sulfate proteoglycans (HSPGs) on the surface of host hepatocytes.

1. Tan, J. et al. (2018) Nature medicine 24, 401-407. PMID: 29554084
2. Oyen, D. et al. (2020) PLoS pathogens 16, e1008373. PMID: 32150583
Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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