Anti-Rabies Virus (RV) Glycoprotein (G) Dog IgG ELISA Kit (AK584048)

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Overview

Catalog No.	AK584048
Description	Anti-Rabies Virus (RV) Glycoprotein (G) Dog IgG ELISA Kit (AK584048) — Quantitative sandwich ELISA for Anti-Rabies Virus (RV) Glycoprotein (G) Dog IgG. Sample: Plasma, Serum. Range: 1.56 - 100 ng/mL. Sensitivity: 1.09 ng/mL. Highlights ●Sandwich Format — High specificity, reliable quantification. ●High Sensitivity — Optimized for low-abundance target detection. ●Ready-to-Use — Complete kit with pre-coated plates included.
Sample type	Serum, plasma, and other biological fluid samples
Sensitivity	0.77 ng/mL
Range	1.56 - 100 ng/mL
Species reactivity	Rabies virus (RABV)
Target	Glycoprotein
Applications	ELISA
Detection method	Colorimetric
Assay type	Indirect
Recovery	80-120%
Shipping	2-8 ℃
Stability and Storage	The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.
Specifications	Glycoprotein
Background	Envelope glycoprotein (GP) is a ~74 kDa protein. Trimeric GP1,2 complexes form the virion surface spikes and mediate the viral entry processes, with GP1 acting as the receptor-binding subunit and GP2 as the membrane fusion subunit. At later times of infection, down-regulates the expression of various host cell surface molecules that are essential for immune surveillance and cell adhesion. Down-modulates several integrins including ITGA1, ITGA2, ITGA3, ITGA4, ITGA5, ITGA6, ITGAV and ITGB1. This decrease in cell adhesion molecules may lead to cell detachment, contributing to the disruption of blood vessel integrity and hemorrhages developed during infection (cytotoxicity) (Probable). Interacts with host TLR4 and thereby stimulates the differentiation and activation of monocytes leading to bystander death of T-lymphocytes. 1. Simmons, G. et al. (2002) Journal of virology 76, 2518-28. PMID: 11836430 2. Takada, A. et al. (2000) Virology 278, 20-6. PMID: 11112476 3. Iampietro, M. et al. (2017) PLoS pathogens 13, e1006397. PMID: 28542576 4. Edri, A. et al. (2018) Frontiers in immunology 9, 1428. PMID: 30013549 5. Vande Burgt, NH. et al. (2015) Viruses 7, 5587-602. PMID: 26516900 6. Brinkmann, C. et al. (2016) Journal of virology 90, 11075-11086. PMID: 27707924 7. González-Hernández, M. et al. (2018) Journal of virology 92. PMID: 29669839 8. Rizk, MG. et al. (2017) Journal of virology 91. PMID: 28878074
Note	For Research Use Only.

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Datasheet

Anti-Rabies Virus (RV) Glycoprotein (G) Dog IgG ELISA Kit.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Formula

C₁ × V₁ = C₂ × V₂

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Stock Solution

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Working Solution

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Anti-Rabies Virus (RV) Glycoprotein (G) Dog IgG ELISA Kit (AK584048)

Overview

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References

Datasheet

SDS