

| Catalog No. | VK805024 | ||||||
|---|---|---|---|---|---|---|---|
| Description |
Anti-SARS-CoV-2 Nucleoprotein Polyclonal Antibody (VK805024) is a rabbit polyclonal antibody detecting Nucleoprotein. Suitable for Severe acute respiratory syndrome coronavirus 2, Bat coronavirus HKU3, Bat coronavirus 279/2005, Severe acute respiratory syndrome coronavirus, and Bat coronavirus Rp3/2004.
Highlights
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| Species reactivity | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) | ||||||
| Applications | ELISA, IHC, WB | ||||||
| Host species | Rabbit | ||||||
| Isotype | IgG | ||||||
| Clonality | Polyclonal | ||||||
| Immunogen | E. coli - derived recombinant SARS-CoV-2 Nucleoprotein (Asn47-Ala173). | ||||||
| Target | N, NC, Nucleocapsid protein, Nucleoprotein, Protein N | ||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||
| Purification | Purified by antigen affinity column. | ||||||
| Accession | P0DTC9 | ||||||
| Form | Liquid | ||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. | ||||||
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. | ||||||
| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||
| Background | Nucleoprotein is a ~45 kDa protein. Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Attenuates the stress granules formation by reducing host G3BP1 access to host mRNAs under stress conditions. 1. Dinesh, DC. et al. (2020) PLoS pathogens 16, e1009100. PMID: 33264373 2. Nabeel-Shah, S. et al. (2022) iScience 25, 103562. PMID: 34901782 3. Dolliver, SM. et al. (2022) PLoS pathogens 18, e1011041. PMID: 36534661 | ||||||
| Note | For research use only |




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