Anti-Siltuximab Neutralizing Monoclonal Antibody (1A456) (HY328045)

Name: Anti-Siltuximab Neutralizing Monoclonal Antibody (1A456)
Brand: abinScience
SKU: HY328045
Price: 168 USD
Availability: InStock

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Overview

Catalog No.	HY328045
Description	Anti-Siltuximab Neutralizing Antibody (1A456) [1A456] (HY328045) is a mouse monoclonal antibody in ELISA.
Species reactivity	General
Applications	ELISA
Host species	Mouse
Isotype	IgG1
Clone ID	1A456
Clonality	Monoclonal
Immunogen	E. coli - derived recombinant protein.
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P05231
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	Interleukin-6 is a ~23 kDa protein. Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable). The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells (Probable).
Note	For research use only.