Anti-Yellowfever mosquito Aed a 2/AeD7L1 Polyclonal Antibody (JN845014)

Name: Anti-Yellowfever mosquito Aed a 2/AeD7L1 Polyclonal Antibody
Brand: abinScience
SKU: JN845014
Price: 168 USD
Availability: InStock

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SDS

Overview

Catalog No.

JN845014

Description

Anti-Yellowfever mosquito Aed a 2/AeD7L1 Polyclonal Antibody (JN845014) is a rabbit polyclonal antibody detecting Aed a 2 in ELISA, IHC, WB. Suitable for Aedes aegypti.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Aedes aegypti (Yellowfever mosquito)

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Yellowfever mosquito Aed a 2/AeD7L1 (Ser18-Gln321).

Target

Long form salivary protein D7L1, AeD7, AeD7L1, 37 kDa salivary gland allergen Aed a 2, Protein D7, Aed a 2, D7, D7L1, AAEL006424, Aed a 2

Purification

Purified by antigen affinity column.

Accession

P18153

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Long form salivary protein D7L1 (Aed a 2/AeD7L1) is a ~36 kDa protein. Modulates blood feeding of female mosquitoes on vertebrate species by binding and sequestering different mediators involved in the host response, such as biogenic amines and eicosanoids. Binds serotonin, histamine, leukotriene B4, leukotriene C4, leukotriene D4, leukotriene E4, adrenaline and noradrenaline. Does not bind tryptamine and U-46619, a stable analog of thromboxane A2. Exhibits vasodilating activity. Inhibits agonist-induced platelet aggregation but not blood clotting.

1. Martin-Martin, I. et al. (2021) The FEBS journal 288, 2014-2029. PMID: 32799410

2. Martin-Martin, I. et al. (2023) mBio 14, e0228923. PMID: 37909749

3. Calvo, E. et al. (2006) The Journal of biological chemistry 281, 1935-42. PMID: 16301315

4. Calvo, E. et al. (2009) Proceedings of the National Academy of Sciences of the United States of America 106, 3728-33. PMID: 19234127

Note

For research use only.

Images

References

Datasheet

Anti-Yellowfever mosquito Aed a 2/AeD7L1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Yellowfever mosquito Aed a 2/AeD7L1 Polyclonal Antibody (JN845014)

Overview

Images

References

Datasheet

SDS

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