Clazakizumab ELISA Kit (DY328018)

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Overview

Catalog No.	DY328018
Description	Clazakizumab ELISA Kit (DY328018) — Quantitative competitive ELISA for Clazakizumab. Sample: Plasma, Serum. Range: 0.31-5 μg/mL. Sensitivity: 0.156 μg/ml. Highlights ●Competitive Format — High specificity, reliable quantification. ●High Sensitivity — Optimized for low-abundance target detection. ●Ready-to-Use — Complete kit with pre-coated plates included.
Sample type	Plasma, Serum
Sensitivity	19.26 ng/ml
Range	78.13-5,000 ng/ml
Accession	P05231
Applications	ELISA
Detection method	Colorimetric
Assay type	Quantitative
Recovery	70-130%
Shipping	2-8 ℃
Stability and Storage	The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.
Specifications	Clazakizumab
Alternate Names	ALD-518, BMS-945429, 1236278-28-6
Background	Interleukin-6 (Clazakizumab) is a ~23 kDa protein. Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable). The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells (Probable).
Note	For Research Use Only.