HEK293T Human ROR2/NTRKR2 Stable Cell Line (HX930818)

Overview

Catalog No.	HX930818
Description	HEK293T Human ROR2/NTRKR2 Stable Cell Line (HX930818) is a stable cell line expressing ROR2/NTRKR2. Engineered for consistent, high-level target expression in research applications. Highlights ●Stable Expression — Engineered for consistent, high-level target expression.
Accession	Q01974
Applications	FCM
Species	Human
Host species	HEK293T
Target	ROR2/NTRKR2
Properties	Growth Properties: Adherent; Selection Marker: Puromycin (1 μg/mL)
Stability and Storage	Frozen in liquid nitrogen.
Specifications	1 vial contains at least 2×10^6 cells in 1 mL Freeze Medium
Background	Tyrosine-protein kinase transmembrane receptor ROR2 (NTRKR2) is a ~104 kDa protein. Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development. Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation. In contrast, has also been shown to have very little tyrosine kinase activity in vitro. May act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling. 1. Liu, Y. et al. (2007) Molecular endocrinology (Baltimore, Md.) 21, 3050-61. PMID: 17717073 2. Bainbridge, TW. et al. (2014) PloS one 9, e102695. PMID: 25029443

Images

Flow cytometry

Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human ROR2 monoclonal antibody at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.

References

Datasheet