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Ifabotuzumab ELISA Kit (DB681018)

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Overview
Catalog No.DB681018
Description
Ifabotuzumab ELISA Kit (DB681018) — Quantitative sandwich ELISA for Ifabotuzumab. Sample: Plasma, Serum. Range: 0.31-5 μg/mL. Sensitivity: 0.156 μg/ml.
Highlights
  • Sandwich Format — High specificity, reliable quantification.
  • High Sensitivity — Optimized for low-abundance target detection.
  • Ready-to-Use — Complete kit with pre-coated plates included.
Sample typePlasma, Serum
Sensitivity0.156 μg/ml
Range0.31-5 μg/mL
Accession P29320
Applications ELISA
Detection method Colorimetric
Assay type Quantitative
Recovery 80-120%
Shipping 2-8 ℃
Stability and Storage The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.
Specifications

Ifabotuzumab

Alternate NamesFibatuzumab, KB-004, , 1234137-51-9
Background

Ephrin type-A receptor 3 (Ifabotuzumab) is a ~110 kDa protein. Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Highly promiscuous for ephrin-A ligands it binds preferentially EFNA5. Upon activation by EFNA5 regulates cell-cell adhesion, cytoskeletal organization and cell migration. Also activated by EFNA1, inhibiting epithelial-to-mesenchymal transition of cardiac cells and playing a role in heart development.

1. Lawrenson, ID. et al. (2002) Journal of cell science 115, 1059-72. PMID: 11870224
2. Sharfe, N. et al. (2003) Journal of immunology (Baltimore, Md. : 1950) 170, 6024-32. PMID: 12794130
Note For Research Use Only.
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References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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