InVivoMAb Anti-Staphylococcus aureus Alpha‑Toxin/Hla Antibody (Iv0192) (JN998010)

Name: InVivoMAb Anti-Staphylococcus aureus Alpha‑Toxin/Hla Antibody (Iv0192)
Brand: abinScience
SKU: JN998010
Price: 370 USD
Availability: InStock

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Overview

Catalog No.	JN998010
Description	InVivoMAb Anti-Staphylococcus aureus Alpha-toxin/hly Antibody (Iv0192) [Iv0192] (JN998010) is a human monoclonal antibody detecting Alpha-hemolysin in ELISA, Neutralization.
Species reactivity	Staphylococcus aureus
Applications	ELISA, Neutralization
Host species	Human
Isotype	IgG1, kappa
Clone ID	Iv0192
Clonality	Monoclonal
Target	Alpha-hemolysin, Alpha-HL, Alpha-toxin, hly, hla, Staphylococcus aureus
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Associated products	pH 7.4 Dilution Buffer
Purification	Protein A/G purified from cell culture supernatant.
Accession	P09616
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	Alpha-hemolysin (Alpha-toxin/hly) is a ~35 kDa protein. Alpha-toxin binds to the membrane of eukaryotic cells (particularly red blood cells, RBC) forming pores, resulting in hemolysis, with the release of low-molecular weight molecules leading to eventual osmotic RBC lysis. Human RBCs bind much less alpha-toxin than do rabbit RBCs. Heptamer oligomerization and pore formation is required for lytic activity. 1. Walker, B. et al. (1992) The Journal of biological chemistry 267, 10902-9. PMID: 1587866 2. Wilke, GA. et al. (2010) Proceedings of the National Academy of Sciences of the United States of America 107, 13473-8. PMID: 20624979
Note	For research use only. Not suitable for clinical or therapeutic use.