HBoV1 Minor capsid VP1 Recombinant Protein (N-His) (VK140012)

Name: HBoV1 Minor capsid VP1 Recombinant Protein (N-His)
Brand: abinScience
SKU: VK140012
Price: 211 USD
Availability: InStock

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Catalog No.	VK140012
Description	Recombinant HBoV1 Minor capsid protein VP1, N-His (VK140012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	Q3YPH4
Protein length	Lys181-Gly290
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Primate bocaparvovirus 1 (Human bocavirus 1 type 1) (HBoV1)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	EC:3.1.1.4, Minor capsid protein VP1, VP1
Background	Minor capsid protein VP1 is a ~75 kDa protein. Capsid proteins self-assembles to form an icosahedral capsid with a T=1 symmetry, about 26 nm in diameter, and consisting of 60 copies of three size variants of the capsid proteins, VP1, and VP3, which differ by the presence of an N-terminal extension in the minor protein VP1 (Probable). The capsid has a channel at the 5-fold axis and there are densities extending the 5-fold axis into the interior of the capsid. The capsid encapsulates the genomic ssDNA (Probable). Binding to the host receptors also induces capsid rearrangements leading to surface exposure of VP1 N-terminus, specifically its phospholipase A2-like region. The additional N-terminal region of isoform Minor capsid protein VP1, called VP1u, may serve as a lipolytic enzyme to breach the endosomal membrane during entry into host cell and might contribute to virus transport to the nucleus. 1. Mietzsch, M. et al. (2017) Journal of virology 91. PMID: 28331084
Note	For research use only

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HBoV1 Minor capsid VP1 Recombinant Protein (N-His).pdf

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HBoV1 Minor capsid VP1 Recombinant Protein (N-His) (VK140012)

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