HSV-2/HHV-2 glycoprotein H/gH Recombinant Protein (N-His) (VK081022)

Name: HSV-2/HHV-2 glycoprotein H/gH Recombinant Protein (N-His)
Brand: abinScience
SKU: VK081022
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	VK081022
Description	Recombinant HSV-2/HHV-2 glycoprotein H/gH, N-His (VK081022) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	P89445
Protein length	Arg49-Pro803
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Human herpesvirus 2 (HHV-2) (Human herpes simplex virus 2) (HSV-2)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	Envelope glycoprotein H, gH
Background	Envelope glycoprotein H is a ~89 kDa protein. The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Following initial binding to host receptor, membrane fusion is mediated by the fusion machinery composed of gB and the heterodimer gH/gL. May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis. Interaction with host integrins ITGAV/ITGB3 triggers release of cytosolic Ca(2+) and FAK phosphorylation leading to efficient viral entry into host genital tract epithelial cells. 1. Cheshenko, N. et al. (2014) Journal of virology 88, 10026-38. PMID: 24942591
Note	For research use only

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Datasheet

HSV-2/HHV-2 glycoprotein H/gH Recombinant Protein (N-His).pdf

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HSV-2/HHV-2 glycoprotein H/gH Recombinant Protein (N-His) (VK081022)

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