Human ADRB1 Recombinant Protein (N-His-KSI) (HY486012)

Name: Human ADRB1 Recombinant Protein (N-His-KSI)
Brand: abinScience
SKU: HY486012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HY486012
Description	Recombinant Human ADRB1 Protein, N-His-KSI (HY486012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	P08588
Protein length	Gly2-Gln55&His197-Arg222
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	ADRB1, ADRB1R, B1AR, Beta-1 adrenergic receptor, Beta-1 adrenoceptor, Beta-1 adrenoreceptor
Background	Beta-1 adrenergic receptor is a ~51 kDa protein. G protein-coupled receptor for catecholamines that couples to G(s) proteins to activate adenylate cyclase and cAMP-dependent pathway. Binds epinephrine and norepinephrine with approximately equal affinity. Mediates the activation of Ras via binding with cAMP-dependent RAPGEF2. As part of the sympathetic nervous system, plays a role in the physiologic regulation of cardiac functions such as stimulation of cardiomyocyte contraction. Also delivers proapoptotic signals in cardiomyocytes. 1. Mason, DA. et al. (1999) The Journal of biological chemistry 274, 12670-4. PMID: 10212248 2. Pak, Y. et al. (2002) Molecular and cellular biology 22, 7942-52. PMID: 12391161 3. He, J. et al. (2004) The Journal of biological chemistry 279, 50190-6. PMID: 15358775 4. Xu, X. et al. (2021) Cell research 31, 569-579. PMID: 33093660 5. Börjesson, M. et al. (2000) European heart journal 21, 1853-8. PMID: 11052857 6. Ranade, K. et al. (2002) American journal of human genetics 70, 935-42. PMID: 11854867 7. Shi, G. et al. (2019) Neuron 103, 1044-1055.e7. PMID: 31473062
Note	For research use only

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SDS-PAGE for Human ADRB1 Recombinant Protein (N-His-KSI)

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Datasheet

Human ADRB1 Recombinant Protein (N-His-KSI).pdf

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Human ADRB1 Recombinant Protein (N-His-KSI) (HY486012)

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