Human CD83 Recombinant Protein (C-Fc) (HX237021)

Name: Human CD83 Recombinant Protein (C-Fc)
Brand: abinScience
SKU: HX237021
Price: 298 USD
Availability: InStock

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Overview

Catalog No.	HX237021
Description	Recombinant Human CD83 Protein, C-Fc (HX237021) expressed in Mammalian Cells, spanning Met1-Ala143. Purity: >90% by SDS-PAGE. Highlights ●Fc Fusion — Enhanced stability with Protein A/G purification compatibility. ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	Mammalian cells
Accession	Q01151
Protein length	Met1-Ala143
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	42.46 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	B-cell activation protein, CD83, CD83 antigen, Cell surface protein HB15, hCD83
Background	CD83 antigen is a ~23 kDa protein. Transmembrane glycoprotein predominantly found on the surface of many immune cells including dendritic cells or lymphocytes that plays various roles in immune response regulation. Plays an essential role in CD4(+) T-selection, differentiation and stability by regulating the activity of the major E3 ubiquitin ligase responsible for controlling MHCII trafficking MARCHF8. Also inhibits MARCHF1 association with MHCII or CD86 to prevent their ubiquitination and subsequent degradation. In addition, acts as an important modulator of protective responses against acute infections. 1. Tze, LE. et al. (2011) The Journal of experimental medicine 208, 149-65. PMID: 21220452
Note	For research use only

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Datasheet

Human CD83 Recombinant Protein (C-Fc).pdf

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Formula

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C₁ × V₁ = C₂ × V₂

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Human CD83 Recombinant Protein (C-Fc) (HX237021)

Overview

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Datasheet

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