Human CMKLR2 Recombinant Protein (N-His-KSI) (HD623012)

Name: Human CMKLR2 Recombinant Protein (N-His-KSI)
Brand: abinScience
SKU: HD623012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HD623012
Description	Recombinant Human CMKLR2 Protein, N-His-KSI (HD623012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	P46091
Protein length	Glu2-Ser41&Ser308-Gln355
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	CMKLR2, Chemerin chemokine-like receptor 2, Chemerin-like receptor 2, Chemokine-like receptor 2, G-protein coupled receptor 1, GPR1
Background	Chemerin-like receptor 2 is a ~41 kDa protein. Receptor for chemoattractant adipokine chemerin/RARRES2 suggesting a role for this receptor in the regulation of inflammation and energy homesotasis. Signals mainly via beta-arrestin pathway. Binding of RARRES2 activates weakly G proteins, calcium mobilization and MAPK1/MAPK3 (ERK1/2) phosphorylation too. Also acts as a receptor for TAFA1, mediates its effects on neuronal stem-cell proliferation and differentiation via the activation of ROCK/ERK and ROCK/STAT3 signaling pathway. 1. Barnea, G. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 64-9. PMID: 18165312 2. De Henau, O. et al. (2016) PloS one 11, e0164179. PMID: 27716822
Note	For research use only

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Datasheet

Human CMKLR2 Recombinant Protein (N-His-KSI).pdf

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Human CMKLR2 Recombinant Protein (N-His-KSI) (HD623012)

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