Human ENPP7 Recombinant Protein (C-Fc) (HD356011)

Name: Human ENPP7 Recombinant Protein (C-Fc)
Brand: abinScience
SKU: HD356011
Price: 298 USD
Availability: InStock

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Overview

Catalog No.	HD356011
Description	Recombinant Human ENPP7 Protein, C-Fc (HD356011) expressed in Mammalian Cells, spanning Met1-Pro421. Purity: >90% by SDS-PAGE. Highlights ●Fc Fusion — Enhanced stability with Protein A/G purification compatibility. ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	Mammalian cells
Accession	Q6UWV6
Protein length	Met1-Pro421
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	74.07 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	Alk-SMase, Alkaline sphingomyelin phosphodiesterase, E-NPP 7, EC:3.1.4.12, ENPP7, Ectonucleotide pyrophosphatase/phosphodiesterase family member 7, Intestinal alkaline sphingomyelinase, NPP-7
Background	Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 is a ~51 kDa protein. Choline-specific phosphodiesterase that hydrolyzes sphingomyelin releasing the ceramide and phosphocholine and therefore is involved in sphingomyelin digestion, ceramide formation, and fatty acid (FA) absorption in the gastrointestinal tract. Also has phospholipase C activity and can also cleave phosphocholine from palmitoyl lyso-phosphatidylcholine and platelet-activating factor (PAF) leading to its inactivation. Does not have nucleotide pyrophosphatase activity. May promote cholesterol absorption by affecting the levels of sphingomyelin derived from either diet or endogenous sources, in the intestinal lumen. 1. Duan, RD. et al. (2003) Journal of lipid research 44, 1241-50. PMID: 12671034 2. Duan, RD. et al. (2003) The Journal of biological chemistry 278, 38528-36. PMID: 12885774 3. Wu, J. et al. (2004) American journal of physiology. Gastrointestinal and liver physiology 287, G967-73. PMID: 15205117 4. Wu, J. et al. (2006) The Biochemical journal 394, 299-308. PMID: 16255717 5. Gorelik, A. et al. (2017) The Journal of biological chemistry 292, 7087-7094. PMID: 28292932
Note	For research use only

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Datasheet

Human ENPP7 Recombinant Protein (C-Fc).pdf

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Human ENPP7 Recombinant Protein (C-Fc) (HD356011)

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