Human GPR25 Recombinant Protein (N-His-KSI) (HD143012)

Name: Human GPR25 Recombinant Protein (N-His-KSI)
Brand: abinScience
SKU: HD143012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HD143012
Description	Recombinant Human GPR25 Protein, N-His-KSI (HD143012) expressed in E. coli. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	O00155
Protein length	Ala2-Val40&Ala96-Ala127&Val176-Gly201&Leu263-Thr290&Leu310-Trp361
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	34.90 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	GPR25, Probable G-protein coupled receptor 25
Background	C-X-C chemokine receptor GPR25 is a ~38 kDa protein. Receptor for the C-X-C chemokine CXCL17, which plays a key role in lymphocyte homing. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as RhoA pathway. Activation by CXCL17 on lymphocytes activates the RhoA pathway, which regulates cytoskeletal dynamics and integrins, mediating lymphocyte recruitment into the respiratory, upper gastrointestinal, biliary and genito-urinary tracts. 1. Ocón, B. et al. (2024) Nature 635, 736-745. PMID: 39293486 2. Hu, WF. et al. (2025) The FEBS journal 292, 5998-6015. PMID: 40279398
Note	For research use only

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Datasheet

Human GPR25 Recombinant Protein (N-His-KSI).pdf

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Human GPR25 Recombinant Protein (N-His-KSI) (HD143012)

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