

| Catalog No. | HD429012 |
|---|---|
| Description |
Recombinant Human HSD17B2 Protein, N-His (HD429012) expressed in E. coli, spanning Asp81-Thr387. Purity: >90% by SDS-PAGE.
Highlights
|
| Expression system | E. coli |
| Accession | P37059 |
| Protein length | Asp81-Thr387 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Species | Homo sapiens (Human) |
| Nature | Recombinant |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >90% as determined by SDS-PAGE. |
| Predicted molecular weight | 36.19 kDa |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | 17-beta-HSD 2, 17-beta-hydroxysteroid dehydrogenase type 2, 20 alpha-hydroxysteroid dehydrogenase, 20-alpha-HSD, E2DH, EC:1.1.1.239, EC:1.1.1.62, EDH17B2, Estradiol 17-beta-dehydrogenase 2, HSD17B2, Microsomal 17-beta-hydroxysteroid dehydrogenase, SDR9C2, Short chain dehydrogenase/reductase family 9C member 2, Testosterone 17-beta-dehydrogenase |
| Background | 17-beta-hydroxysteroid dehydrogenase type 2 is a ~42 kDa protein. Catalyzes the NAD-dependent oxidation of the highly active 17beta-hydroxysteroids, such as estradiol (E2), testosterone (T), and dihydrotestosterone (DHT), to their less active forms and thus regulates the biological potency of these steroids. Oxidizes estradiol to estrone, testosterone to androstenedione, and dihydrotestosterone to 5alpha-androstan-3,17-dione. Also has 20-alpha-HSD activity. |
| Note | For research use only |
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