Human LACTB Recombinant Protein (N-His) (HD571012)

Name: Human LACTB Recombinant Protein (N-His)
Brand: abinScience
SKU: HD571012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HD571012
Description	Recombinant Human LACTB Protein, N-His (HD571012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	P83111
Protein length	Cys100-Ser256
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	EC:3.4.-.-, LACTB, MRPL56, Serine beta-lactamase-like protein LACTB, mitochondrial
Background	Serine beta-lactamase-like protein LACTB, mitochondrial is a ~60 kDa protein. Mitochondrial serine protease that acts as a regulator of mitochondrial lipid metabolism. Acts by decreasing protein levels of PISD, a mitochondrial enzyme that converts phosphatidylserine (PtdSer) to phosphatidylethanolamine (PtdEtn), thereby affecting mitochondrial lipid metabolism. It is unclear whether it acts directly by mediating proteolysis of PISD or by mediating proteolysis of another lipid metabolism protein. Acts as a tumor suppressor that has the ability to inhibit proliferation of multiple types of breast cancer cells: probably by promoting decreased levels of PISD, thereby affecting mitochondrial lipid metabolism. 1. Keckesova, Z. et al. (2017) Nature 543, 681-686. PMID: 28329758
Note	For research use only

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Datasheet

Human LACTB Recombinant Protein (N-His).pdf

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Human LACTB Recombinant Protein (N-His) (HD571012)

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