Human LDLRAD4 Recombinant Protein (N-His-KSI) (HD518012)

Name: Human LDLRAD4 Recombinant Protein (N-His-KSI)
Brand: abinScience
SKU: HD518012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HD518012
Description	Recombinant Human LDLRAD4 Protein, N-His-KSI (HD518012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	O15165
Protein length	Leu86-Val306
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	C18orf1, LDLRAD4, Low-density lipoprotein receptor class A domain-containing protein 4
Background	Low-density lipoprotein receptor class A domain-containing protein 4 is a ~33 kDa protein. Functions as a negative regulator of TGF-beta signaling and thereby probably plays a role in cell proliferation, differentiation, apoptosis, motility, extracellular matrix production and immunosuppression. In the canonical TGF-beta pathway, ZFYVE9/SARA recruits the intracellular signal transducer and transcriptional modulators SMAD2 and SMAD3 to the TGF-beta receptor. Phosphorylated by the receptor, SMAD2 and SMAD3 then form a heteromeric complex with SMAD4 that translocates to the nucleus to regulate transcription. Through interaction with SMAD2 and SMAD3, LDLRAD4 may compete with ZFYVE9 and SMAD4 and prevent propagation of the intracellular signal.
Note	For research use only

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Datasheet

Human LDLRAD4 Recombinant Protein (N-His-KSI).pdf

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Formula

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Human LDLRAD4 Recombinant Protein (N-His-KSI) (HD518012)

Overview

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References

Datasheet

SDS

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