

| Catalog No. | HB622012 |
|---|---|
| Description |
Recombinant Human NTSR1 Protein, N-His-KSI (HB622012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| Expression system | E. coli |
| Accession | P30989 |
| Protein length | Arg2-Thr67&Asn365-Tyr418 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Species | Homo sapiens (Human) |
| Nature | Recombinant |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >90% as determined by SDS-PAGE. |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | High-affinity levocabastine-insensitive neurotensin receptor, NT-R-1, NTR1, NTRH, NTRR, NTSR1, Neurotensin receptor type 1 |
| Background | Neurotensin receptor type 1 is a ~46 kDa protein. G-protein coupled receptor for the tridecapeptide neurotensin (NTS). Signaling is effected via G proteins that activate a phosphatidylinositol-calcium second messenger system. Signaling leads to the activation of downstream MAP kinases and protects cells against apoptosis. 1. Heakal, Y. et al. (2011) Cancer biology & therapy 12, 427-35. PMID: 21725197 2. Da Costa, G. et al. (2013) Journal of biomolecular structure & dynamics 31, 1381-92. PMID: 23140271 3. Vita, N. et al. (1993) FEBS letters 317, 139-42. PMID: 8381365 |
| Note | For research use only |
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