Human PTK2B Recombinant Protein (N-His) (HC433012)

Name: Human PTK2B Recombinant Protein (N-His)
Brand: abinScience
SKU: HC433012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HC433012
Description	Recombinant Human PTK2B Protein, N-His (HC433012) expressed in E. coli, spanning Gly21-Thr409. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	Q14289
Protein length	Gly21-Thr409
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	47.25 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	CADTK, CAK-beta, CAKB, Calcium-dependent tyrosine kinase, Calcium-regulated non-receptor proline-rich tyrosine kinase, Cell adhesion kinase beta, EC:2.7.10.2, FADK 2, FAK2, Focal adhesion kinase 2, PTK2B, PYK2, Proline-rich tyrosine kinase 2, Protein-tyrosine kinase 2-beta, RAFTK, Related adhesion focal tyrosine kinase
Background	Protein-tyrosine kinase 2-beta is a ~115 kDa protein. Non-receptor protein-tyrosine kinase that regulates reorganization of the actin cytoskeleton, cell polarization, cell migration, adhesion, spreading and bone remodeling. Plays a role in the regulation of the humoral immune response, and is required for normal levels of marginal B-cells in the spleen and normal migration of splenic B-cells. Required for normal macrophage polarization and migration towards sites of inflammation. Regulates cytoskeleton rearrangement and cell spreading in T-cells, and contributes to the regulation of T-cell responses. Promotes osteoclastic bone resorption; this requires both PTK2B/PYK2 and SRC.
Note	For research use only

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Human PTK2B Recombinant Protein (N-His).pdf

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Human PTK2B Recombinant Protein (N-His) (HC433012)

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