

| Catalog No. | MV400012 |
|---|---|
| Description |
Recombinant Mouse CD300A Protein, N-His (MV400012) expressed in E. coli, spanning Pro31-Pro138. Purity: >90% by SDS-PAGE.
Highlights
|
| Expression system | E. coli |
| Accession | Q6SJQ0 |
| Protein length | Pro31-Pro138 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Species | Mus musculus (Mouse) |
| Nature | Recombinant |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >90% as determined by SDS-PAGE. |
| Predicted molecular weight | 14.46 kDa |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | CD300 antigen-like family member A, CD300A, CD300a, CLM-8, CMRF-35-H9, CMRF35-H, CMRF35-H9, CMRF35-like molecule 8, CMRF35H, IGSF12, IRC1/IRC2, IRp60, IgSF12, Immunoglobulin superfamily member 12, Inhibitory receptor protein 60, NK inhibitory receptor |
| Background | CMRF35-like molecule 8 is a ~35 kDa protein. Inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation. Negatively regulates the Toll-like receptor (TLR) signaling mediated by MYD88 but not TRIF through activation of PTPN6. 1. Yotsumoto, K. et al. (2003) The Journal of experimental medicine 198, 223-33. PMID: 12874256 2. Kumagai, H. et al. (2003) Biochemical and biophysical research communications 307, 719-29. PMID: 12893283 3. Bachelet, I. et al. (2005) Journal of immunology (Baltimore, Md. : 1950) 175, 7989-95. PMID: 16339535 |
| Note | For research use only |
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