Mouse CD31/PECAM1 Recombinant Protein (C-His) (MB004011)

Name: Mouse CD31/PECAM1 Recombinant Protein (C-His)
Brand: abinScience
SKU: MB004011
Price: 298 USD
Availability: InStock

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Overview

Catalog No.	MB004011
Description	Recombinant Mouse CD31/PECAM1 Protein, C-His (MB004011) expressed in Mammalian Cells, spanning Glu18-Lys590. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	Mammalian cells
Accession	Q08481
Protein length	Glu18-Lys590
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Mus musculus (Mouse)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	67.43 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	CD31, EndoCAM, GPIIA', PECA1, PECAM-1, PECAM1, Platelet endothelial cell adhesion molecule
Background	Platelet endothelial cell adhesion molecule is a ~81 kDa protein. Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions. Tyr-679 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes. Trans-homophilic interaction may play a role in endothelial cell-cell adhesion via cell junctions. Heterophilic interaction with CD177 plays a role in transendothelial migration of neutrophils. Homophilic ligation of PECAM1 prevents macrophage-mediated phagocytosis of neighboring viable leukocytes by transmitting a detachment signal. 1. Stevens, HY. et al. (2008) Disease models & mechanisms 1, 175-81; discussion 179. PMID: 19048083
Note	For research use only

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SDS-PAGE

SDS-PAGE for Recombinant Mouse CD31/PECAM1 Protein, C-His

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Datasheet

Mouse CD31/PECAM1 Recombinant Protein (C-His).pdf

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Mouse CD31/PECAM1 Recombinant Protein (C-His) (MB004011)

Overview

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Datasheet

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