Mouse VISTA/B7-H5/PD-1H Recombinant Protein (C-Fc) (MP543021)

Name: Mouse VISTA/B7-H5/PD-1H Recombinant Protein (C-Fc)
Brand: abinScience
SKU: MP543021
Price: 298 USD
Availability: InStock

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Overview

Catalog No.	MP543021
Description	Recombinant Mouse VSIR/VISTA Protein, C-Fc (MP543021) expressed in Mammalian Cells, spanning Phe33-Ala191. Purity: >90% by SDS-PAGE. Highlights ●Fc Fusion — Enhanced stability with Protein A/G purification compatibility. ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	Mammalian cells
Accession	Q9D659
Protein length	Phe33-Ala191
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Mus musculus (Mouse)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	46.10 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	C10orf54, Platelet receptor Gi24, SISP1, Sisp-1, Stress-induced secreted protein-1, V-set domain-containing immunoregulatory receptor, V-set immunoregulatory receptor, V-type immunoglobulin domain-containing suppressor of T-cell activation, VISTA, VSIR
Background	V-type immunoglobulin domain-containing suppressor of T-cell activation is a ~33 kDa protein. Immunoregulatory receptor which inhibits the T-cell response. May promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling. May stimulate MMP14-mediated MMP2 activation. 1. Wang, L. et al. (2011) The Journal of experimental medicine 208, 577-92. PMID: 21383057 2. Flies, DB. et al. (2014) The Journal of clinical investigation 124, 1966-75. PMID: 24743150 3. Wang, L. et al. (2014) Proceedings of the National Academy of Sciences of the United States of America 111, 14846-51. PMID: 25267631 4. Aloia, L. et al. (2010) The Journal of biological chemistry 285, 7776-83. PMID: 20042595
Note	For research use only

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Datasheet

Mouse VISTA/B7-H5/PD-1H Recombinant Protein (C-Fc).pdf

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Mouse VISTA/B7-H5/PD-1H Recombinant Protein (C-Fc) (MP543021)

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