

| Catalog No. | HF862996 |
|---|---|
| Description |
Aldafermin (HF862996) is a research-grade recombinant antibody targeting FGF19. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| Species reactivity | Human |
| Applications | ELISA, Functional assay, Research in vivo |
| Isotype | Recombinant human FGF19 analogs. |
| Expression system | Mammalian cells |
| Target | FGF19, Fibroblast growth factor 19, FGF-19 |
| Endotoxin level | Please contact the lab for this information. |
| Purity | >95% purity as determined by SDS-PAGE. |
| Purification | Purified by Nickel column. |
| Accession | O95750 |
| Form | Liquid |
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | NGM282 |
| Background | Fibroblast growth factor 19 (FGF19) is a ~24 kDa protein. Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4. |
| Note | For research use only. Not suitable for clinical or therapeutic use. |

SDS-PAGE for Research Grade Aldafermin




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