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Research Grade Anti-Flu A (H3N2) HA/Hemagglutinin Broadly Neutralizing Antibody (CR8020) (VK515096)

Research Grade Anti-Flu A (H3N2) HA/Hemagglutinin Broadly Neutralizing Antibody (CR8020)
Research Grade Anti-Flu A (H3N2) HA/Hemagglutinin Broadly Neutralizing Antibody (CR8020)
Price(USD): $
Spec:
  • 100ug
  • 1mg
Number:
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Overview
Catalog No.VK515096
Description
Anti-Flu A (H3N2) HA/Hemagglutinin Broadly Neutralizing Antibody (CR8020) (VK515096) is a research-grade recombinant antibody targeting Hemagglutinin. Produced in mammalian cells with native-like glycosylation.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
  • Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivityInfluenza A virus (strain A/Hong Kong/1/1968 H3N2)
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host speciesHuman
IsotypeIgG1-lambda
Clone IDCR8020
Expression system Mammalian Cells
Target Hemagglutinin, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, HA
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q91MA7
Form Liquid
Storage buffer 0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Background

Hemagglutinin (HA) is a ~63 kDa protein. Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.

Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Research Grade Anti-Flu A (H3N2) HA/Hemagglutinin Broadly Neutralizing Antibody (CR8020)

    SDS-PAGE

    SDS-PAGE for Research Grade Anti-Flu A (H3N2) HA/Hemagglutinin Broadly Neutralizing Antibody (CR8020)

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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