Influenza A virus HA/Hemagglutinin Neutralizing Reference Antibody (CR8043, RUO) (VK515136)

Name: Influenza A virus HA/Hemagglutinin Neutralizing Reference Antibody (CR8043, RUO)
Brand: abinScience
SKU: VK515136
Price: 370 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

VK515136

Description

Research Grade Anti-Flu A (H3N2) HA/Hemagglutinin Neutralizing Antibody (CR8043) [H3N2] (VK515136) is a human monoclonal antibody detecting Hemagglutinin in ELISA, WB, SPR, FCM.

Highlights

●Multi-Application — Validated across multiple applications.
●Flow Cytometry — Validated for flow cytometry applications.

Species reactivity

Influenza A virus (H3N2), Influenza A virus (H7N7)

Applications

ELISA, WB, SPR, FCM

Host species

Human

Clonality

Monoclonal

Isotype

IgG1, kappa

Clone ID

CR8043, RUO

Target

HA, Hemagglutinin, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain

Endotoxin level

< 10 EU/mg

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Form

Liquid

Storage buffer

0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Hemagglutinin is a ~63 kDa protein. Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.

Note

For research use only

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