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Anti-Human Complement C3 Reference Antibody (NGM621, RUO) (HF636046)

Anti-Human Complement C3 Reference Antibody (NGM621, RUO)
Anti-Human Complement C3 Reference Antibody (NGM621, RUO)
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Overview
Catalog No.HF636046
Description
Anti-Human Complement C3 Antibody (NGM621) (HF636046) is a research-grade recombinant antibody targeting C3. Produced in mammalian cells with native-like glycosylation.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
  • Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivityHuman
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host speciesHuman
IsotypeIgG
Clone IDNGM621
Expression system Mammalian cells
Target C3, ASP, Complement C3, C3adesArg, C3bc, CPAMD1, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P01024
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate NamesNGM621, NGM621, NGM-621
Background

Complement C3 is a ~187 kDa protein. Precursor of non-enzymatic components of the classical, alternative, lectin and GZMK complement pathways, which consist in a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system.

Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Anti-Human Complement C3 Reference Antibody (NGM621, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Anti-Human Complement C3 Antibody (NGM621)

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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