Anti-Human PIGF Reference Antibody (RO5323441, RUO) (HW315036)

Name: Anti-Human PIGF Reference Antibody (RO5323441, RUO)
Brand: abinScience
SKU: HW315036
Price: 176 USD
Availability: InStock

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Overview

Catalog No.	HW315036
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG
Clone ID	RO5323441
Expression system	Mammalian cells
Clonality	Monoclonal
Target	PLGF, PGF, PlGF, PGFL, Placenta growth factor
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P49763
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	RO5323441
Background	Placenta growth factor (PGF/PLGF) is a ~24 kDa protein. Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth.
References	1. Rizzo C, et al. RO5323441, a humanized monoclonal antibody against the placenta growth factor, blocks PlGF-induced VEGFR-1 phosphorylation in vitro and tumor growth in vivo[J]. Cancer Research, 2010, 70(8_Supplement): 1370-1370. [HW315036]
Note	For research use only. Not suitable for clinical or therapeutic use.