Anti-Human TSG101 Reference Antibody (FGI-101-1A6, RUO) (HV181016)

Name: Anti-Human TSG101 Reference Antibody (FGI-101-1A6, RUO)
Brand: abinScience
SKU: HV181016
Price: 176 USD
Availability: InStock

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Overview

Catalog No.	HV181016
Description	Anti-Human TSG101 (FGI-101-1A6) (HV181016) is a research-grade recombinant antibody targeting Tumor susceptibility gene 101 protein. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG
Clone ID	FGI-101-1A6
Expression system	Mammalian cells
Clonality	Monoclonal
Target	Tumor susceptibility gene 101 protein, ESCRT-I complex subunit TSG101, TSG101
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q99816
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	FGI-101-1A6, FGI1011A6, FGI1011A6
Background	Tumor susceptibility gene 101 protein (TSG101) is a ~43 kDa protein. Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. 1. Baietti, MF. et al. (2012) Nature cell biology 14, 677-85. PMID: 22660413 2. Nabhan, JF. et al. (2012) Proceedings of the National Academy of Sciences of the United States of America 109, 4146-51. PMID: 22315426
Note	For research use only. Not suitable for clinical or therapeutic use.