Research Grade Bevifimod (JN856016)

Name: Research Grade Bevifimod
Brand: abinScience
SKU: JN856016
Price: 370 USD
Availability: InStock

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Overview

Catalog No.	JN856016
Description	Research Grade Bevifimod (JN856016) is a rabbit polyclonal antibody detecting Immunoglobulin G-binding protein A in Functional assay.
Applications	Functional assay
Clonality	Monoclonal
Expression system	Mammalian cells
Nature	Recombinant
Target	Immunoglobulin G-binding protein A, IgG-binding protein A, Staphylococcal protein A, SpA, spa
Endotoxin level	< 10 EU/mg as determined by LAL method.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P38507
Form	Liquid
Storage buffer	0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	Immunoglobulin G-binding protein A is a ~55 kDa protein. Plays a role in the inhibition of the host innate and adaptive immune responses. Possesses five immunoglobulin-binding domains that capture both the fragment crystallizable region (Fc region) and the Fab region (part of Ig that identifies antigen) of immunoglobulins. In turn, Staphylococcus aureus is protected from phagocytic killing via inhibition of Ig Fc region. In addition, the host elicited B-cell response is prevented due to a decrease of antibody-secreting cell proliferation that enter the bone marrow, thereby decreasing long-term antibody production. Inhibits osteogenesis by preventing osteoblast proliferation and expression of alkaline phosphatase, type I collagen, osteopontin and osteocalcin.
Note	For research use only. Not suitable for clinical or therapeutic use.

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Datasheet

Research Grade Bevifimod.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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C₁ × V₁ = C₂ × V₂

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Recombinant Proteins

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Research Grade Bevifimod (JN856016)

Overview

Images

References

Datasheet

SDS