Anti-Human CD74 Reference Antibody (Bezetabart, RUO) (HY465046)

Name: Anti-Human CD74 Reference Antibody (Bezetabart, RUO)
Brand: abinScience
SKU: HY465046
Price: 176 USD
Availability: InStock

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SDS

Overview

Catalog No.	HY465046
Description	Bezetabart (HY465046) is a research-grade recombinant antibody targeting CD74. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
Host species	Human
Clonality	Monoclonal
Isotype	IgG1-kappa
Expression system	Mammalian cells
Nature	Recombinant
Target	HLA-DR antigens-associated invariant chain, HLA class II histocompatibility antigen gamma chain, CD74, CLIP, Ia antigen-associated invariant chain, DHLAG, Ii
Endotoxin level	< 10 EU/mg as determined by LAL method.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P04233
Form	Liquid
Storage buffer	0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	2763746-69-4
Background	HLA class II histocompatibility antigen gamma chain (CD74) is a ~33 kDa protein. Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF.
Note	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

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SDS-PAGE

SDS-PAGE for Research Grade Bezetabart.
Bioactivity

Detects recombinant human CD74 (Catalog No: HY465011) in indirect ELISA
Bioactivity

Detects recombinant CD74 (Catalog No: HY465011) in indirect ELISA.

References

Datasheet

Anti-Human CD74 Reference Antibody (Bezetabart, RUO).pdf

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Recombinant Proteins

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Anti-Human CD74 Reference Antibody (Bezetabart, RUO) (HY465046)

Overview

Images

References

Datasheet

SDS