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Anti-Human Common beta Chain Reference Antibody (Birinkibart, RUO) (HW498036)

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Anti-Human Common beta Chain Reference Antibody (Birinkibart, RUO)

Anti-Human Common beta Chain Reference Antibody (Birinkibart, RUO)

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Spec:

100ug
1mg

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.	HW498036
Description	birinkibart (HW498036) is a research-grade recombinant antibody targeting CD131. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG4, Kappa
Species	Human
Clonality	Monoclonal
Target	CD131/CSF2RB
Purity	>95% as determined by SDS-PAGE.
Accession	P32927
Form	Liquid
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	2894136-82-2
Background	Cytokine receptor common subunit beta (CD131/CSF2RB) is a ~97 kDa protein. Cell surface receptor that plays a role in immune response and controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells. Acts by forming an heterodimeric receptor through interaction with different partners such as IL3RA, IL5RA or CSF2RA. In turn, participates in various signaling pathways including interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor/CSF2 pathways. In unstimulated conditions, interacts constitutively with JAK1 and ligand binding leads to JAK1 stimulation and subsequent activation of the JAK-STAT pathway. 1. Tavernier, J. et al. (1992) Proceedings of the National Academy of Sciences of the United States of America 89, 7041-5. PMID: 1495999 2. Ogata, N. et al. (1998) Blood 91, 2264-71. PMID: 9516124
Note	For research use only. Not suitable for clinical or therapeutic use.

Images

SDS-PAGE

SDS-PAGE for Research Grade birinkibart

References

Datasheet

Anti-Human Common beta Chain Reference Antibody (Birinkibart, RUO).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Formula

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Stock Solution

C₁ (Stock Conc.)

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Working Solution

C₂ (Working Conc.)

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Anti-Human Common beta Chain Reference Antibody (Birinkibart, RUO)