Research Grade Efprezimod alfa (HB630036)

Name: Research Grade Efprezimod alfa
Brand: abinScience
SKU: HB630036
Price: 176 USD
Availability: InStock

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Overview

Catalog No.	HB630036
Description	Research Grade Efprezimod alfa (HB630036) is a human monoclonal antibody detecting Signal transducer CD24 in FuncS. Suitable for Human.
Species reactivity	Human
Applications	FuncS
Host species	Human
Clonality	Monoclonal
Isotype	Fusion - [CD24 (CD24 molecule, CD24 antigen (small cell lung carcinoma cluster 4 antigen))]2 - IGHG1 Fc
Expression system	Mammalian cells
Nature	Recombinant
Target	Signal transducer CD24, Small cell lung carcinoma cluster 4 antigen, CD24, CD24, CD24A
Endotoxin level	< 10 EU/mg as determined by LAL method.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P25063
Form	Liquid
Storage buffer	0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	Signal transducer CD24 (Siglec-10) is a ~8 kDa protein. May have a pivotal role in cell differentiation of different cell types. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells. In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90. 1. Suzuki, T. et al. (2001) Journal of immunology (Baltimore, Md. : 1950) 166, 5567-77. PMID: 11313396
Note	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	VHH-hFc (IgG1) Isotype Control antibody (cAb-Lys2) (ZP167307)

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Datasheet

Research Grade Efprezimod alfa.pdf

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Formula

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Research Grade Efprezimod alfa (HB630036)

Overview

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References

Datasheet

SDS