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Anti-Human Syndecan-1/CD138 Reference Antibody (Indatuximab, RUO) (HB943016)

Anti-Human Syndecan-1/CD138 Reference Antibody (Indatuximab, RUO)
Anti-Human Syndecan-1/CD138 Reference Antibody (Indatuximab, RUO)
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  • Datasheet

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Overview
Catalog No.HB943016
Description
Indatuximab (HB943016) is a research-grade recombinant antibody targeting CD138. Produced in mammalian cells with native-like glycosylation.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
  • Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivityHuman
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host speciesChimeric
IsotypeIgG4-kappa
Expression system Mammalian cells
Clonality Monoclonal
Target CD138, SDC1, SDC, Syndecan-1, SYND1
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P18827
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Syndecan-1 (CD138/SDC1) is a ~32 kDa protein. Cell surface proteoglycan that contains both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP. Able to induce its own expression in dental mesenchymal cells and also in the neighboring dental epithelial cells via an MSX1-mediated pathway.

1. Baietti, MF. et al. (2012) Nature cell biology 14, 677-85. PMID: 22660413
Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Anti-Human Syndecan-1/CD138 Reference Antibody (Indatuximab, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Indatuximab

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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