Anti-Human GDF-8/Myostatin Reference Antibody (Landogrozumab, RUO) (HT343016)

Name: Anti-Human GDF-8/Myostatin Reference Antibody (Landogrozumab, RUO)
Brand: abinScience
SKU: HT343016
Price: 176 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.	HT343016
Description	Landogrozumab (HT343016) is a research-grade recombinant antibody targeting GDF-8. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG4-kappa
Expression system	Mammalian cells
Clonality	Monoclonal
Target	GDF-8, GDF8, MSTN, Myostatin, Growth/differentiation factor 8
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	O14793
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	LY-2495655, 1391726-30-9
Background	Growth/differentiation factor 8 (MSTN/GDF8) is a ~42 kDa protein. Acts specifically as a negative regulator of skeletal muscle growth.
Note	For research use only. Not suitable for clinical or therapeutic use.

Images

Bioactivity

SEC-HPLC detection for Research Grade Landogrozumab.
Flow Cytometry

Flow-cytometry using anti-human MSTN antibody. LNCAP cells were fixed and permeabilized, then stained with an irrelevant antibody (Blue Histogram) or an anti-human MSTN monoclonal antibody (Catalog HT343016, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.
SDS-PAGE

SDS-PAGE for Research Grade Landogrozumab