Anti-Ganglioside GD3 Reference Antibody (Mitumomab, RUO) (YP464026)

Name: Anti-Ganglioside GD3 Reference Antibody (Mitumomab, RUO)
Brand: abinScience
SKU: YP464026
Price: 176 USD
Availability: InStock

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Overview

Catalog No.	YP464026
Description	Mitumomab (YP464026) is a research-grade recombinant antibody targeting Ganglioside GD3. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	General
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Mouse
Isotype	IgG2b-kappa
Expression system	Mammalian cells
Clonality	Monoclonal
Target	Ganglioside GD3
Endotoxin level	< 10 EU/mg
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	BEC2, CAS: 216503-58-1
Background	Mitumomab is an anti-idiotypic mouse IgG2b monoclonal antibody that mimics the ganglioside GD3. Mitumomab can be used for the research of small-cell lung carcinoma. • GD3 ganglioside and apoptosis., PMID:12531552 • Ganglioside GD3: structure, cellular distribution, and possible function., PMID:3903474 • Ganglioside GD3 as a raft component in cell death regulation., PMID:21554197 • A reappraisal of ganglioside GD3 expression in the CNS., PMID:8721669 • Ganglioside GD3 regulates neural stem cell quiescence and controls postnatal neurogenesis., PMID:37667994 • Ganglioside GD3 is up-regulated in microglia and regulates phagocytosis following global cerebral ischemia., PMID:34133773 • Ganglioside GD3 regulates dendritic growth in newborn neurons in adult mouse hippocampus via modulation of mitochondrial dynamics., PMID:32743804 • Possible regulation of ganglioside GD3 synthase gene expression with DNA methylation in human glioma cells., PMID:36897478 • Ganglioside GD3 Regulates Inflammation and Epithelial-to-Mesenchymal Transition in Human Nasal Epithelial Cells., PMID:38612859 • Development of Fluorescent Ganglioside GD3 and GQ1b Analogs for Elucidation of Raft-Associated Interactions., PMID:32951428
Note	For research use only. Not suitable for clinical or therapeutic use.