Anti-Human IL-1Rrp2/IL-1R6 Reference Antibody (Recibokibart, RUO) (HV454016)

Name: Anti-Human IL-1Rrp2/IL-1R6 Reference Antibody (Recibokibart, RUO)
Brand: abinScience
SKU: HV454016
Price: 176 USD
Availability: InStock

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SDS

Overview

Catalog No.	HV454016
Description	recibokibart (HV454016) is a research-grade recombinant antibody targeting IL1RL2/IL-36R. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research.
Species reactivity	Human
Applications	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
Host species	Human
Clonality	Monoclonal
Isotype	IgG1, Kappa
Expression system	Mammalian cells
Nature	Recombinant
Target	IL1RL2/IL-36R
Endotoxin level	< 10 EU/mg as determined by LAL method.
Purity	>95% as determined by SDS-PAGE.
Accession	Q9HB29
Form	Liquid
Storage buffer	0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	2744274-17-5
Background	Interleukin-1 receptor-like 2 (IL1RL2/IL-36R) is a ~65 kDa protein. Receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways. The IL-36 signaling system is thought to be present in epithelial barriers and to take part in local inflammatory response; it is similar to the IL-1 system. Seems to be involved in skin inflammatory response by induction of the IL-23/IL-17/IL-22 pathway.
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE

SDS-PAGE for Research Grade recibokibart

References

Datasheet

Anti-Human IL-1Rrp2/IL-1R6 Reference Antibody (Recibokibart, RUO).pdf

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Formula

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Recombinant Proteins

Antibodies

Assay Kits

Anti-Human IL-1Rrp2/IL-1R6 Reference Antibody (Recibokibart, RUO) (HV454016)

Overview

Images

References

Datasheet

SDS