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Anti-HIV-1 gp120 Reference Antibody (Teropavimab, RUO) (VK617046)

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Anti-HIV-1 gp120 Reference Antibody (Teropavimab, RUO)

Anti-HIV-1 gp120 Reference Antibody (Teropavimab, RUO)

Anti-HIV-1 gp120 Reference Antibody (Teropavimab, RUO)

Anti-HIV-1 gp120 Reference Antibody (Teropavimab, RUO)

Anti-HIV-1 gp120 Reference Antibody (Teropavimab, RUO)

Anti-HIV-1 gp120 Reference Antibody (Teropavimab, RUO)

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Spec:

100ug
1mg

Number:

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.	VK617046
Description	Teropavimab (VK617046) is a research-grade recombinant antibody targeting gp120/Glycoprotein 120. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human immunodeficiency virus 1 (HIV-1)
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Humanized
Isotype	IgG1-kappa
Expression system	Mammalian Cells
Clonality	Monoclonal
Target	gp120/Glycoprotein 120
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q03805
Form	Liquid
Storage buffer	30 mM Histidine, pH5.8, 10% sucrose, 0.02% Tween80 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	3BNC117-LS, GS-54232417213-72-8
Background	Envelope glycoprotein gp160 (gp120/Glycoprotein 120) is a ~96 kDa protein. Envelope glycoprotein gp160: Oligomerizes in the host endoplasmic reticulum into predominantly trimers. In a second time, gp160 transits in the host Golgi, where glycosylation is completed. The precursor is then proteolytically cleaved in the trans-Golgi and thereby activated by cellular furin or furin-like proteases to produce gp120 and gp41.
Note	For research use only. Not suitable for clinical or therapeutic use.

Images

SEC-HPLC

SEC-HPLC detection for Research Grade Teropavimab.
Bioactivity

Detects gp120/Glycoprotein 120 in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Research Grade Teropavimab.

References

Datasheet

Anti-HIV-1 gp120 Reference Antibody (Teropavimab, RUO).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Formula

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Working Solution

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Anti-HIV-1 gp120 Reference Antibody (Teropavimab, RUO)