Anti-Human 4-1BB/TNFRSF9/CD137&CD3 epsilon&EGFR/EGFRvIII&PD-L1/B7-H1 Multispecific Reference Antibody (Umizortamig, RUO) (HF004466)

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Spec:

100ug
1mg

Number:

Overview
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Datasheet
SDS

Overview

Catalog No.

HF004466

Description

Umizortamig (HF004466) is a research-grade recombinant antibody targeting CD3. Produced in mammalian cells with native-like glycosylation.

Highlights

●Research Grade — For PK/PD studies, assay development, and ADA research.
●Native Glycosylation — Mammalian expression ensures native-like patterns.

Species reactivity

Human

Applications

ELISA, Bioactivity: FACS, Functional assay, Research in vivo, WB

Host species

Human

Isotype

immunoglobulin scFv-G1-scFv-scFv_L-kappa

Expression system

Mammalian Cells

Clonality

Monoclonal

Tested applications

Target

HER1, Receptor tyrosine-protein kinase erbB-1, Proto-oncogene c-ErbB-1, Epidermal growth factor receptor, EGFR, ERBB1, ERBB, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain, B7-H1, Programmed cell death 1 ligand 1, PDCD1 ligand 1, PDCD1L1, B7 homolog 1, PDCD1LG1, PDL1, hPD-L1, Programmed death ligand 1, B7H1, PD-L1, CD274, Tumor necrosis factor receptor superfamily member 9, CD137, 4-1BB ligand receptor, CDw137, TNFRSF9, T-cell antigen ILA, T-cell antigen 4-1BB homolog, ILA

Endotoxin level

Please contact the lab for this information.

Purity

>95% purity as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P00533 & P07766 & Q9NZQ7 & Q07011

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.

Alternate Names

2599198-83-9

Background

Umizortamig is an anti-CD3E/EGFR/TNFRSF9/PD-L1/CD3G monoclonal antibody.

Note

For research use only. Not suitable for clinical or therapeutic use.

Images

SDS-PAGE

SDS-PAGE for Research Grade Umizortamig.
Bioactivity

Detects recombinant CD137 (Catalog No: HC336011) in indirect ELISA.
Bioactivity

Detects recombinant PDL1 (Catalog No: HV974011) in indirect ELISA.
Bioactivity

Detects recombinant ERBB1 (Catalog No: HF004011) in indirect ELISA.
Western blot

Western blot analysis was performed using anti-CD3E monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human CD3E (Catalog No: HY057021)

References

Datasheet

Anti-Human 4-1BB/TNFRSF9/CD137&CD3 epsilon&EGFR/EGFRvIII&PD-L1/B7-H1 Multispecific Reference Antibody (Umizortamig, RUO).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human 4-1BB/TNFRSF9/CD137&CD3 epsilon&EGFR/EGFRvIII&PD-L1/B7-H1 Multispecific Reference Antibody (Umizortamig, RUO) (HF004466)

Overview

Images

References

Datasheet

SDS

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